ABSTRACT
Objective To analyze the impact factors of the ablation rate after cryoablation treatment of soft tissue sarcomas.Methods Data of 60 patients with soft tissue sarcomas who underwent cryoablation treatment were analyzed.One month after cryoablation,CT or MR examination was performed to assess the ablation rate.Then statistical analysis was conducted to observe the impact factors on the ablation rate of cryoablation treatment.Results The univariate analysis showed that the largest diameter of tumor and tumor location were related to the ablation rate after cryoablation (x2 =10.408,P=0.015;x2 =36.778,P =0.006),while multivariate analysis showed that tumor location was the independent impact factor on ablation rate of cryoablation treatment for soft tissue sarcoma (P＜0.05).Conclusion Cryoablation is safe and effective in the treatment of soft tissue sarcomas.Tumor location is an independent impact factor on ablation rate of cryoablation for soft tissue sarcomas.
ABSTRACT
PURPOSE: To investigate the effect of surface fluid on the ablation rate and efficacy of 213-nm solid-state laser during photorefractive keratectomy (PRK). METHODS: Twelve rabbits (24 eyes) underwent myopic PRK for the correction of 10 diopters using 213-nm solid-state laser. Photoablation was performed with removal of corneal surface fluid using the Weckcel(R) sponge every 5 seconds in one eye and without removal of corneal surface fluid in the control eye. The mean central corneal thickness (CCT) was evaluated preoperatively, and at 1 week, 4 weeks postoperatively. RESULTS: The mean CCT of group 1 (with removal of corneal surface fluid) were 361.3+/-13.9 micrometer preoperatively and 321.4+/-18.5 micrometer at 4 weeks postoperatively. The mean CCT of group 2 (without removal of surface fluid) were 358.7+/-8.9 micrometer preoperatively and 338.4+/-12.0 micrometer at 4 weeks postoperatively. The mean ablation depths were 39.8+/-7.4 micrometer in group 1 and 20.3+/-5.8 micrometer in group 2 at 4 weeks postoperatively p<0.05). CONCLUSIONS: Induced corneal surface fluid during PRK may influence the ablation efficacy and accuracy of solid-state laser. This result should be considered in clinical trialswith 213-nm solid-state laser, especially in high myopes.